‘New CRISPR-based system targets amplified antibiotic-resistant genes’


CRISPR is not without risks (Guido4)

COGwriter

Scientists are hoping to help reverse a problem other ‘scientists’ inadvertently caused:

New CRISPR-based system targets amplified antibiotic-resistant genes

December 16, 2019

A research team led by Andrés Valderrama at UC San Diego School of Medicine and Surashree Kulkarni of the Division of Biological Sciences has developed a new CRISPR-based gene-drive system that dramatically increases the efficiency of inactivating a gene rendering bacteria antibiotic-resistant. The new system leverages technology developed by UC San Diego biologists in insects and mammals that biases genetic inheritance of preferred traits called “active genetics.” The new “pro-active” genetic system, or Pro-AG, is detailed in a paper published December 16 in Nature Communications.

Widespread prescriptions of and use in animal food production have led to a rising prevalence of antimicrobial resistance in the environment. Evidence indicates that these environmental sources of antibiotic resistance are transmitted to humans and contribute to the current health crisis associated with the dramatic rise in drug-resistant microbes. Health experts predict that threats from antibiotic resistance could drastically increase in the coming decades, leading to some 10 million drug-resistant disease deaths per year by 2050 if left unchecked.

The core of Pro-AG features a modification of the standard CRISPR-Cas9 gene editing technology in DNA. Working with Escherichia coli bacteria, the researchers developed the Pro-AG method to disrupt the function of a bacterial gene conferring antibiotic resistance. In particular, the Pro-AG system addresses a thorny issue in antibiotic resistance presented in the form of plasmids, circular forms of DNA that can replicate independently of the bacterial genome. https://phys.org/news/2019-12-crispr-based-amplified-antibiotic-resistant-genes.html

So, California scientists hope that this will work.

But their track record with genetic-editing has shown that they can think they know more than they do.

There simply have not been sufficient studies to prove proper safety and health impacts, nor is it practical to do them for the many GMOs scientists have produced. In order to do this, millions of people would need to be involved. And the time period would need to be enough to cover 3-5 generations–it would probably need to take between 200-400 years to be able to have the data to come to a proper scientific conclusion about that. And, of course, that has not happened. Nor will that happen.

Consider also the following about studies on regular food:

November 4, 2019

A major reason why the nutrition science field is in turmoil is because the science itself is so complicated. Researchers can’t feasibly lock up people for decades and meticulously track their diets. Even if they could, people eat so many different foods in different combinations that isolating the impact of one variable is incredibly difficult. https://www.politico.com/news/agenda/2019/11/04/why-we-dont-know-what-to-eat-060299?utm_source=pocket-newtab

If sufficient studies cannot be done on regular foods, how can any claim that GMOs have been sufficiently tested?

Well, the reality is that GMOs have not been.

And that includes trying to deal with pests.

Notice something reported here a few months ago:

Deadly ‘super mosquitoes that are even tougher’ accidentally created by scientists after bungled experiment

Updated September 18, 2019

GENETICALLY modified mosquitoes that were designed by scientists to help populations decrease are actually thriving.

This is according to new research that claims the plan to create gene-hacked mosquitoes that have offspring which die immediately has spectacularly backfired and now scientists don’t know what will happen next.

The modified mosquitoes were released in Jacobina in Brazil and were supposed to mix with the local population and decrease numbers with their weak offspring genetics.

Although the wild population did plummet for a short while, 18 months later it was right back up again.

This is mostly concerning because scientists think the new ‘super mosquitoes’ have properties that might make them harder to kill. …

The offspring of the gene-hacked mosquitoes and the natural ones are thought to be more robust but whether they pose a threat is unknown.

Researcher Jeffrey Powell told News Atlas: “It is the unanticipated outcome that is concerning.” https://www.thesun.co.uk/tech/9947305/deadly-super-mosquitoes-accidentally-created/

So, scientists were concerned about “the unanticipated outcome.” Having mosquitoes that are “more robust” makes them harder to kill and, thus tends to increase their longevity.

I warned about such things with mosquitoes before they happened (see Scientists confirm COGwriter GMO mosquito warning).

Genetic editing of bacteria will result in superbugs. Human scientists simply cannot do enough tests to prevent this from occurring.

Last month, the Continuing Church of God (CCOG) put out the following video on our Bible News Prophecy YouTube channel:

14:06

The US Centers for Disease Control (CDC) released a report in November 2019 that stated that an American died every 15 minutes from an antibiotic-resistant infection. It reported that an additional one dies about every 45 minutes from Clostridioides difficile. Another CDC report warned of the superbug Candida auris. In China, two recently died of the pneumonic plague, whereas in May 2019, to Mongolians died from the bubonic plague after eating a rodent kidney. Dr. Thiel explained that the flu is often associated with pigs and the Ebola virus from eating fruit bats. He also cited scriptures about which animals God said could be eaten and some of which should be avoided. Dr. Thiel also went over an NPR report which stated that more who get the live polio vaccine are paralyzed from that type of polio than the ‘wild’ kind. Dr. Thiel explains some scriptures about preventing disease as well as those that show that humans will not sufficiently repent and solve infectious disease problems before Jesus returns.

Here is a link to our video: Superbugs, antibiotics, and vaccines.

Consider that the Bible warns:

12 There is a way that seems right to a man, But its end is the way of death.  (Proverbs 14:12)

Last June, scientists pointed out at least one risk associated with gene-editing of humans:

New Study Shows Those First-Ever CRISPR Babies Could Be at Risk of Early Death

June 4, 2019

Chinese scientist He Jiankui first brought gene-edited babies into the world …He’s team gene-edited the twin babies – and a third baby due this summer – to knock out a gene called CCR5 in hopes that it would render them immune to HIV.

But according to new research published in the journal Nature Medicine, people with that genome are 21 percent more likely to die before reaching the average life expectancy. …

“What we found is that they had significantly increased mortality,” lead researcher Rasmus Nielsen told NPR. “It’s rather substantial. We were quite surprised the effect was this large.” …

“This is a lesson in humility,” George Daley, dean of Harvard Medical School, told NPR.

“Even when we think we know something about a gene, we can always be surprised and even startled, like in this case, to find out that a gene we thought was protective may actually be a problem.” https://www.sciencealert.com/sadly-the-chinese-crispr-babies-may-be-doomed-to-die-young

Genetic modification research can involve humans.

Frightening, ‘frankenstein-monsters,’ are being worked on in labs.

We also made a video related to that, including the use of simian species:


13:51

BBC reported about what it called an animal that would be half-human and half-pig. Is such a thing possible? Are chimeras for real? What about a “humanzee”? Are scientists really working on these type of creatures? Is this good? Can something truly be half human and half animal? How are humans different from animals? What is the ‘spirit in man’? What is man? Dr. Thiel addresses these issues and more with biblical-based responses.

Here is a link to our video: Half human, half pig: What’s the difference?

The Bible teaches that God made everything to reproduce after its own kind (Genesis 1).

Of course, those of us who believe the Bible should not be surprised that humans are going the wrong way with aspects of genetic research. Notice that the Bible warned about human knowledge increasing and problems in the end time:

6 And the Lord said, “Indeed the people are one and they all have one language, and this is what they begin to do; now nothing that they propose to do will be withheld from them. 7 Come, let Us go down and there confuse their language, that they may not understand one another’s speech.” (Genesis 11:6-7)

4 “But you, Daniel, shut up the words, and seal the book until the time of the end; many shall run to and fro, and knowledge shall increase.” (Daniel 12:4)

1 But know this, that in the last days perilous times will come: 2 For men will be lovers of themselves, lovers of money, boasters, proud, blasphemers, disobedient to parents, unthankful, unholy, 3 unloving, unforgiving, slanderers, without self-control, brutal, despisers of good, 4 traitors, headstrong, haughty, lovers of pleasure rather than lovers of God, 5 having a form of godliness but denying its power. And from such people turn away! (2 Timothy 3:1-6)

How much ‘love’ do scientists have for the inter-spliced animal-human entities they are sometimes creating? Do they not brutally experiment and then destroy most of what they are currently creating that way?

Lest people think that it is only China involved in such things, consider that the first genetically-modified organism released to the human food supply was a type of tomato in 1994 developed in the USA.

The USA has been in the forefront of risking the food supply by pushing GMOs. Nearly all corn and soy beans (about 90%) in the USA are GMO, and there are many other vegetables that are GMO. This is a risk to the food supply.

Working with bacteria and other microorganisms is a for the development of new pestilences. Notice the words of Jesus:

11 And there will be great earthquakes in various places, and famines and pestilences; and there will be fearful sights and great signs from heaven. (Luke 21:11)

Scientists are taking steps that look to be getting closer to causing one or more severe famines or pestilences or both!

This is going the wrong direction. We need to turn away from such.

The GMO driver is pride and money. The Bible warns:

10 For the love of money is a root of all kinds of evil, for which some have strayed from the faith in their greediness, and pierced themselves through with many sorrows. (1 Timothy 6:10)

And that is what is happening in the GMO/CRISPR world to a major degree. Financial and other forms of greed are driving much of this.

THE FACT IS THAT THERE IS NO WAY THAT THE PRO-GMO FORCES CAN HAVE ENOUGH DATA TO PROVE WHAT THEY ARE DOING IS NOT DANGEROUS.

The Bible warns:

20 For since the creation of the world His invisible attributes are clearly seen, being understood by the things that are made, even His eternal power and Godhead, so that they are without excuse, 21 because, although they knew God, they did not glorify Him as God, nor were thankful, but became futile in their thoughts, and their foolish hearts were darkened. 22 Professing to be wise, they became fools, (Romans 1:20-22)

This whole GMO and human editing experiment has had negative consequences and will have more in the future.

Some items of possibly related interest may include:

GMOs and Bible Prophecy What are GMOs? Since they were not in the food supply until 1994, how could they possibly relate to Bible prophecy? Do GMOs put the USA and others at risk? Here is a related YouTube video GMO Risks and the Bible.
Chimeras: Has Science Crossed the Line? What are chimeras?  Has science crossed the line? Does the Bible give any clues? A video of related interest is Half human, half pig: What’s the difference?
Four Horsemen of the Apocalypse What do each of the four horseman of the Apocalypse represent? Have they began their ride? Did Jesus discuss the any of this? Might their rides coincide with the “beginning of sorrows? Do they start their ride prior to the Great Tribulation? Did Nostradamus or any other ‘private prophets’ write predictions that may mislead people so that they may not understand the truth of one or more of the four horseman? There is also a related YouTube video titled The Four Horsemen of the Apocalypse.
The MYSTERY of GOD’s PLAN Why Did God Create Anything? Why did God make you? This free online book helps answers some of the biggest questions that human have, including the biblical meaning of life. Here is a link to three related sermons: Mysteries of God’s Plan, Mysteries of Truth, Sin, Rest, Suffering, and God’s Plan, and The Mystery of YOU.
Just What Do You Mean — Repentance? Do you know what repentance is? Have you truly repented? Repented of what? Herbert W. Armstrong wrote this as a booklet on this important subject.
Is God’s Existence Logical? Is it really logical to believe in God? Yes! Would you like Christian answers to give atheists? This is a free online booklet that deal with improper theories and musings called science related to the origin of the origin of the universe, the origin of life, and evolution. Two animated videos of related interest are also available: Big Bang: Nothing or Creator? and A Lifegiver or Spontaneous Evolution?
What is Your Destiny? Deification? Did the Early Church Teach That Christians Would Become God? What is your ultimate destiny? What does the Bible teach? Is deification only a weird or cultic idea? Are you to rule the universe? Here is a link to the video sermon What is Your Destiny?
Did Early Christians Believe that Humans Possessed Immortality? What does John 3:16, and other writings, tell us? Did a doctrine kept adopted from paganism? Here is a YouTube video titled Are humans immortal?
Christians: Ambassadors for the Kingdom of God, Biblical instructions on living as a Christian This is a scripture-filled booklet for those wishing to live as a real Christian. A related sermon is also available: Christians are Ambassadors for the Kingdom of God.
Why Were You Born? Why did God make you? Herbert W. Armstrong wrote this as a booklet on this important subject. You may also wish to read the article What is Your Destiny? or watch the video, also titled What is Your Destiny?
Building Character: Going on to Perfection Once you have accepted Jesus, do you need to strive for perfection and build character? A related video sermon is available:
Going on to perfection and building character.
What is the Meaning of Life? Who does God say is happy? What is your ultimate destiny? Do you really know? Does God actually have a plan for YOU personally? If you would like to watch videos covering subjects of this article, you can click on the following links: Why YOU? Why Do YOU Suffer? and What is the meaning of your life?

The Gospel of the Kingdom of God This free online pdf booklet has answers many questions people have about the Gospel of the Kingdom of God and explains why it is the solution to the issues the world is facing. Here are links to three related sermons: The World’s False Gospel, The Gospel of the Kingdom: From the New and Old Testaments, and The Kingdom of God is the Solution.



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